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It all depends on your skills as a developer. If you do know how to work with many threads on many cores, I'd go for a cheap xeon/amd server with 2 or 4 cpu sockets to get up to 64 cores, a min of 1 gigabyte of ram per core, A BOOTABLE RAM DISK ON PCI-EXPRESS WITH AUTOMATIC BACKUP ( SSDs are ridiculous and overrated, they burn out so easily and they're not worth the risk for long-term storage purposes) and a fast HD (10k rpm minimum) as storage. For the GPU, honestly, unless you plan on working with CUDA/ opencl, anything is fine because you'd rarely compute on it. But if you will develop GPU-"powered" neural networks and if wattage isn't of a concern for you, given a proper thermal dissipation, there are many AMDs that can pack a punch for little money both in single and double precision. But if you don't know how to take advantage of multithreading and if frameworks are what you have in mind, whatever you buy, as long as it is fast, "it's gonna be fine".